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Better Sensitivity and Accuracy for Mutation Detection

Our exclusive Multiplexed ICE COLD-PCR (MX-ICP) technology
through selective amplification of mutant DNA
preferentially enriches mutant DNA sequences in an excess of wild-type DNA

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discovery services
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Powered Genetic Tests

MX-ICP Detects Mutations Accurately
and Simply to Improve Patient Outcomes

Amplified Sensitivity for Mutation Detection Down to 0.01%

How It Works

Multiplexed ICE COLD-PCR (Improved and Complete Enrichment CO-amplification at Lower Denaturation temperature) technology preferentially enriches mutant DNA sequences in an excess of wild-type DNA through selective amplification of the mutant DNA. The result is up to a 500-fold increase in sensitivity in identifying mutations with the most precise sequence alteration detection rates available—down to .01%.

Up to a 500-Fold Increase in Mutation Detection

MX-ICP technology works on all major platforms

MX-ICP Detects Many More EGFR Deletions than NGS

The MX-ICP Solution

Enable clinically relevant known and unknown mutations rapidly without major costs or impact to current processes

More sensitive, accurate diagnostics

Sample source independent testing

Enables personalized treatment

Easily implemented into any laboratory

Enables more accurate diagnosis & patient outcomes

Platform Independent

Sanger, NGS, BEAMing, COBAS, HRM, DHPLC, DIgital PCR, and Pyro

Who Can Benefit from Our Services and Technology?


Transgenomic will help you detect known and unknown genetic mutations in DNA isolated from blood, serum and other bodily fluids to advance your biomarker development program


If you need to enrich any type of sample for mutant DNA, then take advantage of our proprietary ICE COLD-PCR technology

Clinical Diagnostics

Detecting small amounts of mutant DNA in a liquid or tissue sample can be impossible unless you let our ICE COLD-PCR technology enable you to detect known and unknown mutations with unheard of sensitivity


Transgenomic has made the possibility of true “Liquid Biopsies” a reality for the oncology community with our groundbreaking ICE COLD-PCR

Learn How We Can Provide the Genetic Testing Tools and Services to Meet Your Needs

MX-ICP Technology | Biomarker Discovery | Genetic Assays and Platforms | Patient Testing



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