Latest Presention on MX-ICP

View the latest presentation on Multiplexed ICE COLD-PCR (MX-ICP) for Detection of Low-Level Mutations in Any Liquid Biopsy Sample using Sanger Sequencing, NGS, or ddPCR by Katherine Richardson, Ph.D. V.P., Research & Development

ICEme 10 Exon Kit

$5,895.00

ICEme Multiplex ICE COLD-PCR Mutation Enrichment Kit for 10 exons with positive control and 24 reactions/exon.

ICEme Kit uses Transgenomic’s exclusive Multiplexed ICE COLD-PCR (MX-ICP) technology for the enrichment of mutations in the key cancer-related genes BRAF, EGFR, KRAS, NRAS & PIK3CA that are routinely analyzed in research on Colorectal, NSCLC, Melanoma & Breast cancer.

For Research Use Only. Sale of this product is conditioned on the Limited Use License which you accept by purchasing this product.

SKU: 71600Y. Category: .

Product Description

ICEme Kit, uses Transgenomic’s exclusive Multiplexed ICE COLD-PCR (MX-ICP) technology, for the enrichment of mutations in the key cancer-related genes BRAF, EGFR, KRAS, NRAS & PIK3CA that are routinely analyzed in research on Colorectal, NSCLC, Melanoma & Breast cancer.

ICEme Kit features and benefits include:

  • 100 – ≥500 fold improvement of mutation detection sensitivity of all sequencing platforms (Sanger, NGS, ddPCR etc.)
  • Improves level of mutation detection (LOD) down to 0.01% or 5 copies in 50,000 genomic equivalents
  • Non allele-specific method that amplifies ALL mutations in the region under investigation, while suppressing wild-type alleles.
  • Compatible with DNA isolated from any sample type including liquid biopsies (plasma, urine, CSF) and tissues (fresh, frozen, FFPE, FNAs).

The first release of the ICEme Kit gives you the choice of selecting from 17 Exons:

  • BRAF Exon 11
  • BRAF Exon 15
  • EGFR Exon 12
  • EGFR Exon 18
  • EGFR Exon 19
  • EGFR Exon 20
  • EGFR Exon 21
  • KRAS Exon 2
  • KRAS Exon 3
  • KRAS Exon 4A
  • KRAS Exon 4B
  • NRAS Exon 2
  • NRAS Exon 3
  • NRAS Exon 4A
  • NRAS Exon 4B
  • PIK3CA Exon 9
  • PIK3CA Exon 20

For Research Use Only. Sale of this product is conditioned on the Limited Use License which you accept by purchasing this product.

For product documentation and support, visit the Product Details and Ordering Page.