Transgenomic WAVE Systems offer discovery
and detection of genetic variation at close to 100% sensitivity, making them
among the most sensitive and accurate technologies for detection of known and
unknown mutations and single nucleotide polymorphisms (SNPs). These systems
are used throughout the world to screen for a large variety of diseases.
More than 350 human genes have been screened entirely or partly by
DHPLC.
A multitude of other applications are being used with WAVE Systems in such
diverse areas as plant genomics, microbial
analysis,
and drug sensitivity. With close
to
1,300 installations around the world, the WAVE System technology has
been
accepted worldwide.
WAVE Systems are fully automated, robust, versatile and
cost effective, meeting the critical requirements of leading academic and biopharmaceutical
laboratories. WAVE Systems utilize DHPLC (denaturing high-performance
liquid chromatography) in conjunction with the Transgenomic patented separation
DNASep® Cartridges
for mutation detection.