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Mitochondrial Genome Mutation Scanning

The MitoScreen™ Assay Kit was developed for rapid mutation screening of the entire mitochondrial genome using multiplex DHPLC (denaturing high performance liquid chromatography).

The MitoScreen™ Assay Kit provides all of the reagents and protocols necessary to screen human genomic DNA populations on the WAVE® System for heteroplasmic mutations present in the mitochondrial genome.

Click here to familiarize yourself with the procedure: With Sound or Without Sound

The MitoScreen Assay Kit allows you to:

  • screen the entire mitochondrial genomic in < 8 hours on a WAVE System 3500HT;
  • detect low levels of heteroplasmic mutations;
  • discover known and unknown mutations at very high efficiency using DHPLC;
  • benefit from fully automated, cost effective analysis on the WAVE System.
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